ALL ORGANS SHRINK DUE TO DEPLETION IN HGH UTILIZATION (return to top)
HGH benefits are most significant in the fact that they are able to significantly reverse the shrinkage of all our organs towards the size they were in our younger years and with better function. As we age all of our organs shrink such as the heart, lungs, brain, liver, kidneys, skin, bone and so on and this is largely due to a depletion in the utilization of HGH ( human growth hormone ). Starting at age 21 to 31 Human Growth Hormone (HGH) begins to decline at about 14 percent each decade so that it is reduced by half by the age of sixty. We produce about 500 micrograms at 20 and by age 80 only 20 micrograms. The pituitary gland produces HGH more than any other hormone. Pituitary cells also called somatotrophin make HGH which is also known as somatotrophin. This is released into the blood for only a few minutes and then taken up into the liver where it is converted into growth factors. The most important of these is IGF-1 ( Insulin Growth Factor One ). It is IGF-1 that is used as a measurement rather than HGH itself as to how much HGH is being secreted by the body and it is IGF-1 that is most directly responsible for the benefits mentioned on this site.
NOT AMOUNT OF HGH BUT THE RELEASE AND RECEPTION OF HGH (return to top)
Studies have shown that the aging pituitary somatotrophe cell is still able to release as much GH as the young cell if it is properly stimulated. This means the decline in HGH is not in producing it but in releasing it to be used. Something happens in the feedback between IGF-1 in the liver and hypothalamus gland which sends messages from the outside world by means of light through the eye and so on to the pituitary gland to regulate its release and the release of many other glands in the body. Normally a decline in IGF-1 tells the hypothalamus to tell the pituitary gland to make more HGH. Research shows that somatostatin which is a natural inhibitor of HGH increases with age and that has been verified in old rats which produced as much HGH as young rats when somatostatin was knocked out. Research has also shown that growth hormone releasing hormone (GHRH) which stimulates the release of HGH becomes less responsive to feedback signals which means it is likely that both things are happening. Not only does the amount of HGH decline with age but our tissues fail to respond to HGH that is there so that aging can be viewed as a disease of growth hormone resistance similar to the way type 2 diabetes is a disease of insulin resistance. All of this does not mean that when HGH declines with age, or somatostatin increases, or receptors become less receptive that these obstacles cannot be overcome. Tests show that administration of HGH somehow overcomes all of these things.
1000′S OF STUDIES SHOW HGH BENEFITS ARE EXTENSIVE (return to top)
On July 5, 1990, the prestigious New England Journal of Medicine published a clinical study about 12 men ages 61 to 81 who had flabby frail and fat-bulging bodies who had through the injections of synthetic HGH turned their bodies into their younger former self by 10 to 20 years. In the this conservative medical journal which rarely uses such descriptions, Daniel Rudman, M.D., and his colleagues at the Medical College of Wisconsin wrote: “The effects of six months of human growth hormone on lean body mass and adipose-tissue mass were equivalent in magnitude to the changes incurred during 10 to 20 years of aging.” Following up on this work Rudman gave HGH to 26 elderly men which had re grown livers, spleens, and muscles that had shrunken with age back to their youthful sizes. Also, there was improved muscular strength which can make the difference between being handicapped to not being able to walk and being able and to not being able to feed ones self and being able or in other words between being dependent and and being independent. This landmark discovery was a gate bursting breakthrough that has now resulted in thousands of studies in the world of medical literature documenting the benefits of HGH. The rejuvenating effects of HGH are full covering both form, function, anatomy, physiology, body, and mind. It has even been shown to enliven and change ones personality to being more out going after 3 to 6 months.
Information in my own words taken from a book titled, “Grow Young with HGH” (copyright 1997) by Ronald Klatz, MD